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Low-dose Immunotherapy References

1	de Boissieu D, Dupont C. Sublingual immunotherapy for cow’s milk protein allergy: a preliminary report. Allergy. 2006;61:1238-9.
2	Boris M, et al. Antigen induced asthma attenuated by neutralization therapy. Clin Ecol. 1985;3:59-62.
3	Boris M, Schiff MJ, Weindorf S, Inselman LS. Bronchoprovocation blocked by neutralisation therapy. (Abstract). J Allergy Clin Immunol 1983;71:92.
4	Boris M, Schiff MJ, Weindorf S. Injection of low-dose antigen attenuates the response to subsequent bronchoprovocative challenge. Otolaryngol Head Neck Surg 1988;98:539-45.
5	Enrique E, Cisteró-Bahíma A. Specific immunotherapy for food allergy: basic principles and clinical aspects. Curr Opin Allergy Clin Immunol. 2006;6:466-9.
6	Enrique E, et al. Sublingual immunotherapy for hazelnut food allergy: a randomized, double-blind, placebo-controlled study with a standardized hazelnut extract. J Allergy Clin Immunol. 2005;116:1073-9.
7	Finn R, Battcock TM. A critical study of clinical ecology. Practitioner 1985;229:883-5.
8	Gerdes KA. Provocation/neutralization testing: a look at the controversy. Clin Ecol. 1989;6:21-9.
9	Gerrard JW, King DS. A double-blind study on the value of low-dose immunotherapy in the treatment of asthma and allergic rhinitis. Clin Ecol. 1989;6:43-6.
10	Green M. Sublingual provocative testing for foods and FD&C dyes. Ann Allergy 1974;33:274-81.
11	Kerzl R, et al. Life-threatening anaphylaxis to kiwi fruit: protective sublingual allergen immunotherapy effect persists even after discontinuation [letter]. J Allergy Clin Immunol. 2007;119:507-8.
12	King WP, et al. Provocation/neutralisation: A two-part study. Part I. The intracutaneous provocative food test: a multi-center comparison study. Otolaryngol Head Neck Surg 1988;99:263-71.
13	King WP, et al. Provocation/neutralisation: A two-part study. Part II. Subcutaneous neutralisation therapy: a multi-center study. Otolaryngol Head Neck Surg 1988;99:272-7.
14	Mabray CR, Burditt ML, Martin TL, Jaynes CR, Hayes JR. Treatment of common gynecologic-endocrinologic symptoms by allergy management procedures. Obstet Gynecol 1982;59:560-4.
15	Mempel M, et al. Severe anaphylaxis to kiwi fruit: immunologic changes related to successful sublingual allergen immunotherapy [letter]. J Allergy Clin Immunol. 2003;111:1406-9.
16	Miller JB. A double-blind study of food extract injection therapy: a preliminary report. Ann Allergy 1977;38:185-91.
17	Miller JB. Techniques of immunotherapy. J Nutr Med. 1992;3:211-4.
18	Monro JA. Food allergy in migraine. Proc Nutr Soc. 1983;42:241-6.
19	Monro JA. Provocation tests for food allergy. (Letter).Lancet 1991;338:1204.
20	Morris DL. Use of sublingual antigen in diagnosis and treatment of food allergy. Ann Allergy 1969;27:289-94.
21	Nouri-Aria KT, et al. Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity. J Immunol. 2004;172:3252-9.
22	Nucera E, et al. Immunological aspects of oral desensitization in food allergy. Dig Dis Sci. 2000;45:637-41
23	O'Shea JA, Porter SF. Double-blind study of children with hyperkinetic syndrome treated with multi-allergen extract sublingually. J Learn Disabil. 1981;14:189-91,237.
24	Parke AL, Hughes GRV. Rheumatoid arthritis and food: a case study. Br Med J 1981;282:2027-9.
25	Passalacqua G, Albano M, Fregonese L, et al. Randomised controlled trial of local allergoid immunotherapy on allergic inflammation in mite-induced rhinoconjunctivitis. Lancet 1998;351:629-32.
26	Patriarca G, et al. Oral desensitizing treatment in food allergy: clinical and immunological results. Aliment Pharmacol Ther. 2003;17:459-65.
27	Podell RN. Intracutaneous and sublingual provocation & neutralization. Clin Ecol. 1983;2:13-20.
28	Rapp DJ. Double-blind case report of chronic headache due to foods and air pollution. (Abstract). Ann Allergy 1978;40:289.
29	Rapp DJ. Double-blind confirmation and treatment of milk sensitivity. Med J Aust 1978;1:571-2.
30	Rapp DJ. Herpes progenitalis responding to influenza vaccine. (Abstract). Ann Allergy 1978;40:302.
31	Rapp DJ. Hyperactivity and food allergy: are they related? (Abstract). Ann Allergy 1978;40:297-8.
32	Rapp DJ. A prototype for food sensitivity studies in children. (Abstract). Ann Allergy 1981;47:123-4.
33	Rea WJ, et al. Elimination of oral food challenge reaction by injection of food extracts. Arch Otolaryngol 1984;110:248-52.
34	Scadding GK, Brostoff J. Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite. Clin Allergy. 1986;16:483-91.
35	Schiff MJ, Boris M, Weindorf S. Low doses of animal antigen attenuates the late asthmatic reaction. Otolaryngol Head Neck Surg 1992;107:91-4.
36	Till SJ, et al. Mechanisms of immunotherapy. J Allergy Clin Immunol. 2004;113:1025-34.
37	Trotsky MB. Neurogenic vascular headaches: food and chemical triggers. Ear Nose Throat J 1994;73:228-30,235-6.
38	Van Niekerk CH, DeWet JI. Efficacy of grass-maize pollen oral immunotherapy in patients with seasonal hay-fever: a double-blind study. Clin Allergy. 1987;17:507-13.
39	Viscomi GJ, Bojrab DI. Use of electrocochleography to monitor antigenic challenge in Meniere’s disease. Otolaryngol Head Neck Surg 1992;107:733-7.

Scientific Papers on the Mechanism of Sublingual Immunotherapy
1	Frew AJ, Powell RJ, Corrigan CJ, Durham SR; UK Immunotherapy Study Group. Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol. 2006;117:319-25.
2	Jutel M, Blaser K, Akdis CA. Histamine receptors in immune regulation and allergen-specific immunotherapy. Immunol Allergy Clin North Am. 2006;26:245-59.
3	Krouse JH, Krouse HJ. Modulation of immune mediators with MQT-based immunotherapy. Otolaryngol Head Neck Surg. 2006;134:746-50.
4	Larche M, Akdis CA, Valenta R. Immunological mechanisms of allergen-specific immunotherapy. Nat Rev Immunol. 2006;6:761-71.
5	Larche M. Peptide immunotherapy. Immunol Allergy Clin North Am. 2006;26:321-32.
6	Mascarell L, Van Overtvelt L, Moingeon P. Novel ways for immune intervention in immunotherapy: mucosal allergy vaccines. Immunol Allergy Clin North Am. 2006; 26:283-306.
7	Novak N. Targeting dendritic cells in allergen immunotherapy. Immunol Allergy Clin North Am. 2006;26:307-19.
8	Passalacqua G, Guerra L, Compalati E, Fumagalli F, Cirillo A, Canonica GW. New insights in sublingual immunotherapy. Curr Allergy Asthma Rep. 2006;6:407-12.
9	Peltier J, Ryan MW. Comparison of intradermal dilutional testing with the Multi-Test II applicator in testing for mold allergy. Otolaryngol Head Neck Surg. 2006;134:240-4.
10	Verhagen J, Blaser K, Akdis CA, Akdis M. Mechanisms of allergen-specific immunotherapy: T-regulatory cells and more. Immunol Allergy Clin North Am. 2006;26:207-31.
11	Wilcock LK, Francis JN, Durham SR. IgE-facilitated antigen presentation: role in allergy and the influence of allergen immunotherapy. Immunol Allergy Clin North Am. 2006;26:333-47.
12	Tsitoura DC, Blumenthal RL, Berry G, Dekruyff RH, Umetsu DT. Mechanisms preventing allergen-induced airways hyperreactivity: role of tolerance and immune deviation. J Allergy Clin Immunol. 2000;106:239-46.
13	Di Rienzo V, Pagani A, Parmiani S, Passalacqua G, Canonica GW. Post-marketing surveillance study on the safety of sublingual immunotherapy in pediatric patients. Allergy. 1999;54:1110-3.
14	Di Rienzo V, Pagani A, Parmiani S, Passalacqua G, Canonica GW. Post-marketing surveillance study on the safety of sublingual immunotherapy in pediatric patients. Allergy. 1999;54:1110-3.
15	Hong SJ, Michael JG, Fehringer A, Leung DY. Pepsin-digested peanut contains T-cell epitopes but no IgE epitopes. J Allergy Clin Immunol. 1999;104:473-8.
16	Maguire P, Nicodemus C, Robinson D, Aaronson D, Umetsu DT. The safety and efficacy of ALLERVAX CAT in cat allergic patients. Clin Immunol. 1999;93:222-31.
17	Pierkes M, Bellinghausen I, Hultsch T, Metz G, Knop J, Saloga J. Decreased release of histamine and sulfidoleukotrienes by human peripheral blood leukocytes after wasp venom immunotherapy is partially due to induction of IL-10 and IFN-gamma production of T cells. J Allergy Clin Immunol. 1999;103:326-32.
18	Stampfli MR, Cwiartka M, Gajewska BU, Alvarez D, Ritz SA, Inman MD, et al. Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. Am J Respir Cell Mol Biol. 1999;21:586-96.
19	Kim TS, DeKruyff RH, Rupper R, Maecker HT, Levy S, Umetsu DT. An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production. J Immunol. 1997;158:4137-44.