Pathology

Breakspear Medical Pathology Department

Urinary Polypeptides (IAG)

Idolyl-Acryloylglycine (IAG) can be found in trace amounts in the urine of apparently health normal individuals.  It is a metabolic product of the amino acide trytophan.

Conditions known to have an increased amount of IAG in the urine are:

• Hartnup Disease
• Dietary abnormalities
• Abnormal bacteria in the large bowel
• Autism
• Attention deficit disorder
• Attention deficit hyperactivity disorder
• Dyslexia
• Obsessive compulsive disorder

Conditions in which IAG may occur are:

• Increased intestinal permeability
• Food allergies
• Dietary sulphated deficiency